G3893
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 | Immunofluorescence Microglia in the hippocampus (CA3 region) in rat brain sections are stained with Monoclonal Anti-Glial Fibrillary Acidic Protein, clone No. G-A-5 (Cat. No. G3893) and Goat Anti-Mouse IgG, TRITC (Cat. No. T6528). From Dr. S. Shoham, Herzog Hospital, Dept of Research, Jerusalem, Israel. |
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G3893
Sigma
Monoclonal Anti-Glial Fibrillary Acidic Protein (GFAP) antibody produced in mouse
clone G-A-5, ascites fluid
| Synonym: | Anti-GFAP, Monoclonal Anti-Glial Fibrillary Acidic Protein |
Description
| Immunogen | GFAP from pig spinal cord |
| Specificity | The antibody reacts specifically with GFAP in immunoblotting assays and labels astrocytes, Bergmann glia cells and chondrocytes of elastic cartilage in immunohistochemical staining. The antibody reacts with glial specific antigen in frozen or alcohol-fixed tissue sections. |
Properties
| antibody form | ascites fluid |
| clone | G-A-5 (monoclonal) |
| contains | 15 mM sodium azide |
| species reactivity | pig, rat, human |
| application(s) | immunohistochemistry: 1:400 using rat brain sections (alcohol-fixed) |
| microarray: suitable | |
| isotype | IgG1 |
| Gene Information | human ... GFAP(2670) |
| rat ... Gfap(24387) | |
| shipped in | dry ice |
| storage temp. | −20°C |
Safety
| WGK Germany | 3 |
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References
| reference | Franco, A.J., et al., Morphometric and immunohistochemical study of the reticulum of red deer during prenatal development J. Anat. 205, 277-289, (2004) Abstract |
| Franco, A., et al., Morphometric and immunohistochemical study of the omasum of red deer during prenatal development J. Anat. 206, 543-555, (2005) Abstract | |
| Knight, E.M., et al., Impaired Adult Neurogenesis in the Dentate Gyrus of a Triple Transgenic Mouse Model of Alzheimer’s Disease PLoS ONE 3, e2935, (2008) Abstract | |
| Debus, E., et al., Monoclonal antibodies specific for glial fibrillary acidic (GFA) protein and for each of the neurofilament triplet polypeptides. Differentiation 25, 193-203, (1983) | |
| Franke, F.E., et al., Unexpected immunoreactivities of intermediate filament antibodies in human brain and brain tumors. Am. J. Pathol. 139, 67, (1991) |
